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Figure 3 shows TMA with 110 tissues biopsies, Including 15 normal and 95 neoplastic pancreatic samples that were used to assess at the protein level the differential look of the upregulated CD59 gene and the downregulated XRCC1 gene. Figure 3b and c show reps images of two core biopsies comprising normal and malignant pancreatic tissues respectively, Immunostained combined with anti CD59 antibody. Moderate immunoreactivity was detected in both ductal and acinar portions of the normal exocrine pancreas, and the islets. however,within the other hand, stronger cytoplasmic staining of malignant ducts, there are times when with luminal accentuation, Was seen in almost 60% of the tumour cases. This difference in CD59 protein expression between malignant and normal ducts was statistically substantive (P=0.0137, cubical 3).
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